The results have been presented of the PZA-INH treatment in a group of 22 patients
with far advanced, caviting pulmonary tuberculosis. These Patients had previously
received long-term chemotherapy including INH.
(1) The radiological evaluations were not impressive, and there were only 4 cases
showing slight improvement, 3cases deteriorated after 5-6 months of PZA-INH
treatment.
(2) The occurrence of negative sputum over 6 months was observed in 5 patients,
among which 3 cases showed recurrence of positive sputum after 8-9 months of
negativity.
(3) Among 12 patients, 6(50%) had a decrease in cough, 9(75%) had a decrease of
expectoration, 4(33%) had an increase in appetite, 2(17%) had an increase in weight and
2 febrile cases(38℃), the temperature returned to normal in 1-2 months of treatment.
(4) Evaluating the side reactions : 3 cases showed mild joint pain for a short period
and I cases developed jaundice after 5 months of treatment.
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